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Other signaling pathways that regulate autophagy include the phosphoinositide 3 kinase (PI3K)/Akt pathway, extracellular signal-regulated kinase (ERK) pathway, mitogen-activated protein kinase (MAPK), and Ras pathway [33, 40, 41]

These proteins not only regulate calcium flux, lipid transport, and energy coordination but also act as mediators of signaling pathways related to oxidative stress and the unfolded protein response [57,58,59,60,61,62]

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